A Monash University-led study published in JAMA Neurology finds that menopause is not linked to faster disability progression in women with relapse-onset multiple sclerosis. It is the largest study to date and helps settle earlier, conflicting evidence from much smaller cohorts.
By Monash University – The National Tribune
Using the MSBase Registry and data from eight Australian centres, researchers followed 987 women for just over 14 years; 404 had gone through menopause. They report that disability increases seen around age 50 are likely driven by general ageing rather than menopause itself.
The authors say the results should reassure women and clinicians. While menopausal symptoms can overlap with MS — such as hot flushes, mood changes and urinary issues — management can focus on lifestyle measures and, where appropriate, menopausal hormone therapy or non-hormonal options to improve quality of life.
MS affects three times more women than men and about one in 800 Australians, underscoring the importance of clear guidance for midlife care in MS.
